Ligand-X

Molecular docking

Molecular docking with AutoDock Vina, free on your hardware.

Prepare receptors, find pockets, dock single ligands or libraries, and inspect ranked poses in one self-hosted workbench — no account, no cloud upload.

Preparation, pocket finding, docking, and molecular dynamics are free and always will be.

From raw PDB to ranked poses

Clean the receptor, detect or draw a search box, prepare ligands with Meeko, and run AutoDock Vina with live job progress.

Batch screening in one project

Dock a library against a target, compare affinities and interactions in Mol*, and keep every pose attached to the experiment that produced it.

Continue into dynamics

Send a docked complex straight into OpenMM molecular dynamics — the same free workbench, not a second tool chain.

Frequently asked questions

Is molecular docking free forever?

Yes. Preparation, pocket finding, docking, and molecular dynamics are free and always will be.

Do I need an account or internet for docking?

No account is required. Ligand-X runs locally; after images are pulled you can work offline on your own hardware.

Which docking engine does Ligand-X use?

AutoDock Vina with Meeko ligand preparation, plus optional Vinardo scoring.

Download Ligand-X Docking guide